Blar i forfatter "Lyså, Lena Marianne Myreng"
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HE4 is a novel tissue marker for therapy response and progestin resistance in medium- and low-risk endometrial hyperplasia
Ørbo, Anne; Arnes, Marit; Lyså, Lena Marianne Myreng; Borgfelt, Christer; Straume, Bjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-08-18)Background: The aim of the present study was to investigate whether changes in the tissue expression of human epididymisspecific protein 4 (HE4) could predict therapy resistance and relapse after progestin hormone therapy for medium- and low-risk endometrial hyperplasia.<p> <p>Methods: Endometrial biopsies were obtained from women participating in a multicentre RCT performed according to the ... -
Significance of progesterone receptors (PR-A and PR-B) expression as predictors for relapse after successful therapy of endometrial hyperplasia: a retrospective cohort study
Sletten, Elise Thoresen; Arnes, Marit; Lyså, Lena Marianne Myreng; Larsen, Marthe; Ørbo, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-25)<p><i>Objective - </i>After successful progestin therapy for endometrial hyperplasia (EH), the risk of relapse remains. We aimed to assess if immunohistochemical (IHC) expression of progesterone receptor isoforms, PR‐A and PR‐B, in endometrial glands and stroma in pre‐treatment endometrial biopsies was related to relapse of EH. <p><i>Design and setting - </i>Biopsy material originated from women ...